VenomVet™ is under USDA jurisdiction and not the FDA. VenomVet™ is a product licensed by the USDA based on Clinical Trials conducted under Clinical Trial Protocols reviewed by the USDA and approved for use in field studies to determine both the safety and efficacy on actual canines that were envenomed by Crotalidae. All of the data used in the Clinical Trials was based on actual cases conducted by numerous veterinarians in THREE REGIONS OF THE UNITED STATES. Based on the clinical data submitted to the USDA, U.S. Veterinary Permit No. 444A was issued in April 2014 to MT Venom, LLC for the sale and distribution of VenomVet™ for use by veterinarians only in the treatment of canines envenomed by Crotalidae.


University of Florida College of Veterinary Medicine 

2015 SW 16th AV Gainesville, FL 32610-0126 

Phone: (352) 392-2235 

Fax: (352) 846-2445


Crotalids, also called pit vipers, comprise the largest family of venomous snakes in the United States (Crotalidae). The Crotalidae family includes rattlesnakes, copperheads and cottonmouths.Pit vipers are named for the heat sensitive pits located between the eyes and nostril. They can also be identified by their distinguishing characteristic of triangle shaped heads. These snakes can strike at 8 feet per second and may strike up to one-half of their body length. Crotalids retractable fangs, 10 to 12 mm long, are capable of penetrating 1 to 8 mm deep.With the exception of Maine, Alaska and Hawaii, every state in the United States has at least one type of these venomous snakes. In the United States, 99% of all venomous snake bites are from Crotalids. It is estimated that 150,000 to 300,000 companion animals are bitten by Crotalids every year in the United States with 90% of these bites occurring between April and October. Rattlesnakes account for about 80% of canine envenomations while cottonmouths and copperheads about 20%. In canines, 70 to 80% of snakebites occur on the face and head and 20 to 30% occur on the legs.Crotalidae venom is comprised of enzymes, myotoxins, cytotoxins, hemorrhagic toxins, cardiotoxins and neurotoxins that have a toxic effect on a canine’s physiological systems. The only proven therapy against Crotalidae envenomations is antivenin. In general, antivenin if given early after an envenomation can be effective at reversing the neurological, coagulopathic, cardiovascular and necrotizing effects of venom.